CCN3, the new hope for bone health

A team of researchers from the University of California has discovered a maternal brain hormone, called CCN3, that has the potential to transform the treatment of physical illnesses. Published in the prestigious journal Nature, this troball shows that CCN3 can significantly increase bone mass.

The CCN3 hormone will be identified as a key factor in bone regeneration and fortification. The team, led by Professor Holly Ingraham, is carrying out studies in animal models that will demonstrate a notable increase in bone density thanks to this hormone.

The discovery will be corroborated by an innovative study that will use the parabiosi technique, with two mice being surgical units to share the circulatory system. The results will show that the presence of CCN3 in the cervell of the mouse mutants carried an increase of up to 152% compared to the controls.

“The identification of CCN3 offers new possibilities in the treatment of osteoporosis and other conditions that affect human health”

Holly Ingraham, professor of Molecular Cellular Pharmacology at the University of California.

Researchers hope that these troublings can be translated into clinical treatments for humans, providing new hope for millions of people suffering from debilitating illnesses. This scientific advance not only promises to improve the quality of life of patients, but with additional research and clinical trials, CCN3 could become a fundamental pillar in the fight against physical loss and other related pathologies.

Source: Nature Magazine