A research group in Japan has developed a promising drug that stimulates tooth growth. Although testing in humans has yet to be done, the results obtained in animal studies are encouraging, suggesting that this drug could be available for use in 2025.

The research team, led by Katsu Takahashi from the Department of Dentistry and Oral Surgery at the Kitano Hospital Medical Research Institute, has managed to develop a drug that could achieve the regeneration of teeth, as well as provide a solution to certain rare pathologies that affect children. The primary goal is to provide patients with a third option besides dental implants and dentures to address tooth loss. The study has been published in The Japan Times.

The basis of the drug lies in the suppression of a gene called USAG-1, which is found in mice and affects tooth growth. Inhibition of this gene stimulates tooth regeneration, and the drug developed is a “neutralizing antibody drug.” Trials conducted on mice and ferrets (whose dental patterns are more similar to humans) have demonstrated successful results. The company Toregem Biopharma plans to begin clinical trials in humans, possibly in July next year, which could mark a significant advance in the field of dentistry and offer new hope to those suffering from tooth loss problems and related rare diseases.

Fuente: The Japan Times

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